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            Anterferon® Suppository--Recombinant Human Interferon alpha 2b (rIFN a2b, rDNA Origin) Suppository


            SPECIFICATION AND INTRODUCTION

            [PRODUCT NAME]

            Generic name: Recombinant Human Interferon alpha 2b Vaginal Suppository

            Trade name: Anterferon®

            Chinese phoneticize: Chongzu Ren Ganraosu alpha 2b Shuan

            [COMPOSITION]

            Recombinant Human Interferon alpha 2b

            [DESCRIPTION]

            Milky or light yellow Suppository

            [INDICATIONS]

            Cervical erosion by viral infection

            [VIAL SIZE]

            100000 IU/ pill

            [ADMINISTRATION and DOSAGE]

            Apply to affected vault of vaginal before sleep. Use 1 pill every other day. A normal treatment course need 6~9 pills.

            [ADVERSE REACTIONS]

            Inferior venter swell, lumbago, vaginal prickle, causalgia temperal low ferver, profuse leucorrhea. The symptom may disappear after cessation of therapy.

            [CONTRAINDICATIONS]

            It is contraindicated in those patients who have hypersensitivity to the drugs.

            [PRECAUTIONS]

            1.      Don't use during menstruate.

            2.      Be abstinence during therapy.

            3.      Don't take hip bath during therapy.

            4.      Don't use in pregnant and baby-nursing women.

            5.      The drug may melt if temperature is higher than 30oC. Store at 2~8oC before use.

            [PREGANT AND BREASTFEEDING WOMEN]

            Can't use.

            [PEDIATRICS]

            Experience is limited.

            [OLD PATIENTS]

            Experience is limited.

            [INTERACTION]

            Experience is limited.

            [OVERDOSAGE]

            No serious adverse reactions for overdosage have been reported. Attention should be given to dosage during therapy.

            [PHARMACOLOGICALACTIONS]

            Interferon alpha 2b exerts actions of antiviral and regulating immunity. Such immunomodulation activities include enhancement of the phagocytes for targets cells, and enhancement of the NK cells activities.

            [PHARMACOKINETICS]

            There is no study on this term, please see The Pharmacokinetics Instruction of Recombinant Human Interferon alpha 2b for injection for reference: Cmax of Anterferon is serum occurred at 3.5~8 hours after intramuscular or subcutaneous injection; the half-life of clearance is about 4~12 hours. Kidney is the main organ of clearance. Biliation and metabolism in liver are also important way for elimination of interferon. More than 80% interferon can be absorbed via intramuscular subcutaneous injection.

            [STORAGE]

            Dark at 2~8oC, keep dry.

            [EXPIRY]

            18 months

            [LICENCES NUMBER]

            GYZZS20020103

            [MANUFACTURED BY]

            Anhui Anke Biotechnology (Group) Co., Ltd

            [ADDRESS]

            Ankebio Building, 669 Changjiang Road, West ,Hefei, 230088, P.R. China.

            tel: +86-551-65319890, 65318811

            fax:+86-551-65319895

            e-mail:info@ankebio.com

            http://www.amstyles.com

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